The five-year survival rate for all stages of mucosal melanoma is 14 percent. Melanocytes are the cells in your skin that make melanin. Melanotan II inducing rhabdomyolysis and renal failure have been described previously. Add your thoughts and get the conversation going. nails hands and feet. Hanie Elfenbein, DVM, PhD. 4. 7% were aged 70-79. Melanoma is less common than some other types of skin cancer, but it is more likely to grow and spread. Only about 15% of all melanomas are nodular. This means that with more Melanin present in the body (for all skin types) you could reduce. This critical review aimed to evaluate the current literature and provide treatment recommendations and possible suggestions for future canine OMM research. 2 years ago. Non-V600 BRAF mutated melanomas, compared to those with BRAF V600 mutations or BRAF WT tumors, had higher levels of immune cell infiltration, increased. It was originally designed in the United States and approved by the United States Food and Drug Administration for women with hypoactive sexual desire disorder. About 7,990 people are expected to die of melanoma (about 5,420 men and 2,570 women). Spread of pigment from the border of a mole into the surrounding skin. Melanoma is a skin cancer that can show up on the skin in many ways. The association with MC analogs and painful erection encourage its role as a screening tool in the history. 23. Nasal Melanotan is 30% less effective than tan injections Great for holidays or top ups With UK. Carmela Anthony X (Twitter) Stats and Analytics. Strength. 0 ( 8 reviews ) £ 48. Melanoma, the most serious skin cancer, develops on skin that gets too much sun. Melanotan, an injectable MC analog, is illicitly available on the internet to supplement sunless tan, sexual arousal, and weight loss. A black/dark spot or streak under a fingernail or toenail (that hasn’t come from previous trauma to the nail)Ultraviolet light. Immunotherapy for Melanoma Skin Cancer. If you or someone you care about has been diagnosed with this condition, you may be coping with a lot of difficult questions and concerns — plus the stress of the unknown. Malignant melanoma arises from melanocytes in a pigmented area (eg, skin, mucous membranes, eyes, or central nervous system). Acral lentiginous melanoma (ALM), also sometimes referred to as, simply, acral melanoma, is melanoma occurring on the hands and feet (palms, soles, fingers, toes, and nail units). Tests and procedures used to diagnose melanoma include: Physical exam. Causes and Risk Factors of Nodular Melanoma. The word acral derives from the Greek word referring to the highest or topmost portion of the limbs (extremities). This is repeated until a layer shows no signs of cancer. 173,782 likes · 2,118 talking about this. sunlight. It begins in the melanocytes, which are skin cells that produce a pigment called melanin. Both my husband and I have been using melanotan 2 on and off for 3 years now. Level 2: Melanoma has invaded the papillary dermis (the outermost layer of the dermis, the next layer of skin). Choose an option Melanotan 1 Peptide Melanotan 2 Peptide Melanotan 2 Nasal Spray Melanotan 1 Nasal Spray Melanotan 2 Sublingual Tablets. Medicinal sciences have facilitated us with several drugs to make up for deficiencies that can cause. BRAF V600 mutations have been. • Symptoms include a new, unusual growth or changes to an existing mole on the skin. Melanocortin analogues, such as melanotan, are illegally used for artificial tanning. What you should know: This is the most aggressive type of melanoma. Epibulbar Melanoma. Melanoma that occurs on the skin, called cutaneous melanoma, is the most common type of melanoma. 25 mg) dose = 3 IUs. Således kunne Melanotan give beskyttende hudfarve uden at vinterbleg. Biopsies of areas other than the skin may be needed in some cases. Trusted Source. If the two things you can't live without are a dark, even tan and a fast-acting, long-lasting erection, then add Melanotan II to your holiday shopping list. This makes Melanotan a great option if you're looking for a longer-lasting tan without the hassle of frequent applications. Gastrointestinal issues, including diarrhea and vomiting. 06958-3. Carmela Anthony @melamoans 7 months ago. Week 1. Department of Biomedical Sciences, School of Health Sciences, International Hellenic University, Alexandrian Campus, Sindos, Thessaloniki, Greece - mbobos@icloud. Order: 20 – 49 vials and SAVE 20%. As a rule, the lower the number, the less the cancer has spread. In fact, sometimes it doesn’t have much color at all. It was under development as drug candidate for female sexual dysfunction erectile dysfunction but clinical development ceased by 2003, and as of 2018, no product containing melanotan II was. $ 47. Dome-shaped growth that feels firm and may look like a sore, which. Treatment. Sometimes, the surgeon will create a flap. Melanotan II was originally developed as a “tanning” hormone and researchers also reported increased libido in patients. Sore on the skin that does not heal. take the syringe out of the packaging and push the needle part into the side of the water and fill the syringe with water 1 full syringe is 1ml of water (some people add another quarter. Melanoma is the fifth most common cancer among men and women in the United States. Spot that looks like a new mole, freckle, or age spot, but it looks different from the others on your skin. 00 out of 5 based on 8 customer ratings. We provide the best SARMS and USA Peptides online. About 80% of uveal melanomas are benign (non-cancerous). Unlicensed melanotan injections are illegal to sell in the UK. Other warning signs for foot melanoma include: a sore that does not heal. Some social media influencers have been promoting. Regular self-examination will help you determine if a mole is new or changing. It is twice more common in men and occurs mostly in individuals ≥ 60 years of age. sexyrexy83. When injected into the body, melanotan can stimulate the pigment cells to produce more melanin, which in turn can accelerate tanning. Pigment gives color to your skin, hair and eyes. Melanoma is the most dangerous type of skin cancer. It may also refer to the appearance of metastatic melanoma in other body sites such as skin, lymph nodes, brain, or liver after the initial tumor has already been treated. There isn't enough information to know whether melanotan-II is safe for other. These calculations assume that researchers have access to a syringe size of 1 mL and have reconstituted 10 mg of melanotan 2 with 2 mL of bacteriostatic water: 250 mcg (0. Melanotan 1 (MT-1) is a synthetic equivalent of alpha-melanocyte-stimulating hormone (alpha-MSH). Different. Anorectal melanoma (AM) is a rare malignancy, characterized by aggressive behavior and a poor prognosis. A spot, sore, mole or lump that looks shiny, waxy, smooth or pale. Melanoma is the most dangerous type of skin cancer. flushing. The most common type of melanoma spreads on the skin's surface. Melanotan 2 (MT-2) is a synthetic analogue of alpha-melanocyte-stimulating hormone. Melanoma appears most commonly on the trunk area in fair. These tumors are both locally invasive and have a high tendency to metastasize to other organs. Summary. Melanotan II produces melanogenesis mainly through peripheral MC1R binding. *Bulk discount will be displayed in your shopping cart. The earliest physical evidence of melanoma comes from the diffuse melanotic metastases found in the skeletons of Pre-Colombian mummies (radiocarbon dated to be ~2400 years old) from Chancay and Chingas in Peru ( 7 ). Vairous other melanocortinergic agents are under investigation for enhancement of sexual. 3K followers, 0 /. PubMed, Web of Science and Google Scholar were searched in. There are two forms of melanotan which are known as. Crusting or scabbing can be a melanoma indicator. People of all colors, including those with brown and black skin, get skin cancer. Melanoma is the fourth most common type of cancer diagnosed in Australians after breast, prostate, and colorectal cancers. a mole is bleeding or becoming crusty. La melanina es responsable del color de la piel y del cabello. Oncept is a vaccine that is used to treat melanoma, a cancer of pigmented cells that can spread throughout the body, in dogs and other veterinary species. Alpha-MSH is primarily known for its influence on. When delivered by injection over the course of as little as a week, Melanotan has the effect of (semi-permanently) darkening the skin, as though tanned by the sun. Desmoplastic melanoma (DM) is a variant of spindle cell melanoma typically found on chronically sun-damaged skin of older individuals. ”. Instead of tanning, we encourage people to embrace their natural skin tone, and enjoy the sun safely. Order in bulk and SAVE! Order: 5 – 9 vials and SAVE 10%. melanotan-II. 00. Naturally occurring α-MSH has also been shown to play. Avoid using. ”. Materials and methods: Ten men with erectile dysfunction of no known organic cause were entered in a double-blind, placebo controlled crossover study in which the. The Therapeutic Goods Administration has issued a warning about Melanotan-II, a substance being widely spruiked on social media platforms that promises to give users a tan without the sun — but. Histopathologic classification and prognostic factors of melanoma: a 2021 update. We deliver the highest quality peptides you can buy online. Ocular melanoma (melanoma in or around the eye) is a type of cancer that develops in the cells that produce pigment. On this page. Effectiveness. Although these choroidal melanocytes are similar to those cells found in the skin that produce skin. Sun exposure is still considered to be the major risk factor for melanoma. Melanomas typically occur in the skin, but may rarely occur. brown, black, tan, red, blue, and even white, often. It can also begin in places where the sun rarely shines, such as your foot. If you are experiencing side effects after using these products, please see your healthcare professional. They are generally recognized in older horses but usually begin their development when animals are 3–4 years old. Highest quality SARMS and Peptides for sale, made in the USA with the same day shipping!People with xeroderma pigmentosum, (XP) have a higher risk of developing melanoma and other skin cancers when they’re young, especially on sun-exposed areas of their skin. Learn more about the types of melanoma: in Situ, Superficial Spreading Malignant, Nodular, Lentigo Maligna, Acral Lentiginous Malignant, Ocular, and unknown. Experts are warning Aussies to stay away from a ‘Barbie drug’ tanning product popular on Tiktok, with warnings for those who use it. To learn more about nodular melanoma, as well as how it's diagnosed and. Melanoma is a type of skin cancer. Histologic appearance of LM compared to non-LM melanoma in situ. B, Higher power image of case 1. The primary symptom of amelanotic melanoma is an unusual skin growth. true. k. Medicinal sciences have facilitated us with several drugs to make up for deficiencies that can cause chronicle diseases. The synthetic hormone stimulates the pigment cells, which causes them to. Melanoma is the most serious type of skin cancer. The TGA counterpart in the United. We have become the nation’s leading source for buying USA peptides, research chemicals and Liquid SARMS. Melanotan 2, often abbreviated as Mt2, is a lab-based chemical created to mimic the composition and effects of the naturally occurring hormone called alpha-melanocyte-stimulating hormone (α-MSH). Visit us to schedule a free 15-minute health advisor call to discuss your health needs and goals: Website: melanomas are the most common eye tumors in dogs. having a lot of moles (naevi) – more than 50 on the body and more than 10 above the elbows on the arms. 99 $ 37. 7 years among men and 62. Lentigo maligna melanomas are most often found in adults on the arms, legs, face, neck and other areas exposed to the sun. Unlike cutaneous melanoma which is most frequently distributed on photo-exposed areas (face, trunk, lower limbs) making it possible to diagnose it from early stages, vulvar and vaginal melanomas have origins that are generally overlooked by frequent inspection, the anatomical position of the lesion being the main. Central nervous system (CNS) melanoma is a rare malignancy accounting for approximately 1% of all melanoma cases, whereas primary spinal melanoma (PSM). Since the 1960s, its incidence has increased steadily, in 2019, with. We would like to show you a description here but the site won’t allow us. Symptoms of melanoma. Melanotan 2 is a peptide research chemical to help with tanning and is popular in the bodybuilding community. Naturally occurring α-MSH has also. We happily pass those savings on to you, our valued and loyal customers. In the last decades, CM’s incidence has gradually risen, with 351,880 new cases in 2015. Urgent warning about tanning product Melanotan-II. The cause and outcome of renal infarction is not well established and is frequently misdiagnosed or diagnosed late. Melanoma, also redundantly known as malignant melanoma, is a type of cancer that develops from the pigment-producing cells known as melanocytes. Some consider. That is a typical insulin needle used to mix as well as inject. Firm and dome-shaped. We supply Melanotan 2 all over the world, without restrictions. Melanomas on the sun-exposed skin were further divided by the histopathologic degree of cumulative solar damage (CSD) of the. A new spot on the skin or a spot that is changing in size, shape, or color is an important warning sign. In most cases, melanomas have an irregular shape and. Important Points to Remember. Stage 2: These melanomas are greater than 1 mm, with or without ulceration. What It Is: “Acral” comes from the Greek word akron, meaning extremity, and this fourth type of skin melanoma typically appears on the palms, on the soles, or under the nails. If left out of the fridge in warm conditions dispose of the Melanotan after 12hrs. Alpha-MSH is primarily known for its influence on. 8% of all mucosal melanomas, and 1% of all anorectal malignant tumors. Out of 699 patients with melanoma included in the study, 26 (3. Volunteer Support MKM. It is localized but invasive, meaning that it has penetrated beneath the top layer into the next layer of skin. Sunlight is the main source of UV rays. Afamelanotide, sold under the brand name Scenesse, is a medication used to prevent phototoxicity and to reduce pain from light exposure for people with erythropoietic protoporphyria. Although it is available to purchase online, melanotan is illegal, untested and unregulated. There are 5 stages of melanoma, from 0 to 4. The risk of melanoma increases with age. Background: Melanotan II (MT II) is a synthetic analogue of α-melanocyte-stimulating hormone that, via interaction with the melanocortin 1 receptor, induces skin hyperpigmentation. pigment spreading from the border of a lesion to the surrounding skin. 1st and 3rd Party Verified for 99% Purity. The short answer is a firm and unequivocal no. Since the abnormal cells in melanoma create pigment, most of the time, with melanoma you’ll develop one or more tumors that are black or brown. Ocular Melanoma: found on a dog’s eyelids or directly on the eye. Estos melanomas ocultos son más frecuentes en personas que tiene la piel más oscura. This type is rare. [2] Globally, in 2012, it newly occurred in 232,000 people. tan. Amelanotic melanomas: Growths with no color at all or sometimes appearing slightly pink in color. Order: 10 – 19 vials and SAVE 15%. Dark skin next to your nail. As cancer researchers. Check your skin for any unusual changes. 16mg/kg per day for up to 10 days [ 4 ]. Melanoma is a type of skin cancer. Sometimes, however. Although most melanomas arise in the skin, they may also arise from mucosal surfaces or at other sites to which neural crest cells migrate, including the uveal tract. Areas of white, gray, red, pink, or blue may also be seen. Melanomas can vary greatly in how they look. a mole looks inflamed. Estas células producen un pigmento en la piel llamado melanina. Accounting for 3. New. a. with qualified orders over $500 USD. The TGA has previously warned consumers against the use of Melanotan-I and Melanotan-II for tanning and weight loss. Diameter: There is a change in size, usually an increase. Crusting, bleeding, itching, or stinging. We are proud to offer 99. 4–1. People of all colors, including those with brown and black skin, get skin cancer. Although it is the most common eye cancer in adults. alpha-MSH. enhanced erectile function. Nov. Melanin is the body’s pigment responsible for a photoprotective safe tan. The TGA has previously warned consumers against the use of Melanotan-I and Melanotan-II for tanning and weight loss. Fair-skinned and light-haired persons living in high sun-exposure environments are at greatest risk. It is much more common on the feet than on the hands. There are two forms of melanotan which are known. While there are no known fatalities due to melanotan, daily MT-2 injections over 1mg have been linked to acute side effects, such as priapism requiring medical intervention. It develops from skin cells called melanocytes. Ultraviolet light comes from the sun or sunbeds. Narrator: Melanoma may be diagnosed when a skin irregularity, thought to be a mole, becomes cancerous. Byron says. Any change in size, shape, color or elevation of a spot on your skin, or any new symptom in it, such as bleeding, itching or crusting, may be a warning sign of melanoma. We’ve created a peptide dosage calculator to help you reconstitute your peptides fresh from the source, and then a peptide dosage chart with some common guidelines on dosing, timing, and injection site with all our sources and citations. Your doctor will ask questions about your health history and examine your skin to look for. Coping and support Coping with vision changes. In other cases, they likely happen as the result of exposure to an outside cause. These melanomas grow from the tissues that make up the uvea (the iris, ciliary body, and choroid). Melanoma is more than 20 times more common in White people than in Black people. Melatonin is a well-known natural antioxidant, and has many bioactivities. 08mg/kg to 0. You may see a patch of abnormal skin but not the usual dark brown or black color that usually. But melanoma is not uncommon among people younger than 30. La mayoría de los melanomas tienen un área negra o negra azulada. Melanoma comes from skin cells called melanocytes. 9 percent) of melanomas develop from new growths, and only a minority (29. Your doctor will ask questions about your health history and examine your skin to look for signs that may indicate melanoma. a mole is bleeding or becoming crusty. Tanning injections usually contain a chemical known as melanotan, which is the most popular form of melanin injection in the UK. Although the primary cutaneous melanoma can be managed by surgery, the advanced metastatic melanoma cannot be managed by surgery alone and thus, requires better therapeutic approaches. Melanoma skin cancer. It can causes nausea, stomach cramps, decreased appetite, flushing, tiredness, yawning, darkened skin. Free (1) 30 ml Bacteriostatic Water. Melanotan 2 10mg USA For Sale. Melanoma is a common cancer in the Western world with an increasing incidence. The seriousness of the cancer is based primarily on tumor thickness. Mohs surgery is done by a specially trained dermatologist or surgeon. By increasing melanin production, the skin’s natural pigment becomes darker, or ‘tanned’. Pigment, redness or swelling that spreads outside the border of a spot to the surrounding skin. When delivered by injection over the course of as little as a week, Melanotan has the effect of (semi-permanently) darkening the skin, as though tanned by the sun. For patients diagnosed with stage 4 melanoma (distant spread), the five-year survival rate is 27 percent. 95 $ 47. This page is about melanoma skin cancer. 17, 2022. Information for Oncology Clients Penn Vet Ryan Hospital • 3900 Spruce St. Sexual stimulation and metabolic effects are. One of the key factors dermatologists look for in cancerous moles is changing. If you do drink, have no more than 1. Redness or a new swelling beyond the border of the mole. If you start off with low doses and inject just before you go to sleep you won't feel any side effects. drowsiness. 1 This type of melanoma can occur in any part of the skin, including the soles of feet, on the palms of the hand, in between toes and fingers, and underneath the finger and toe nails. The average age of people diagnosed is 65. e. Load More. A new mole or a change in an existing mole may be signs of melanoma. Learn about the different types of melanoma skin cancer. ”. The extent to which Martina Big has taken her Melanotan usage is obviously next level though. If you notice these warning signs and symptoms, or see anything NEW, CHANGING or UNUSUAL on your skin see a dermatologist promptly. When given as a shot: Melanotan is POSSIBLY UNSAFE when given as a shot. It has fewer side effects than Melanotan 2, but it’s harder to find and is more expensive. We used a maternal immune activation (MIA) mouse model of autism to assess the therapeutic potential of MT-II on autism-like features in adult male mice. 10mg Melanotan II. all the best videos to get ya nut off. Existing mole that begins to change color, size or shape. The two most common types of melanomas are dermal melanomas, which present as small individual tumors,. 74 per million women []. It accounts for 10 to 15 percent of all cases. Cutaneous (skin based) melanomas also occur in cats, mainly on the head or. Overall rating 3. These cells produce melanin, the dark pigment that gives skin its color. For best results, the peptide should be injected just below the skin (subcutaneously). Carmela Anthony retweeted. Learn about melanoma skin cancer risk factors, causes, symptoms, and treatment. 3D animation af Melanotan-1 peptid molekyle. m. Delay: A lesion takes longer than 2 months to heal. Level 3: Melanoma has invaded throughout the papillary dermis and is touching on the next, deeper layer of the dermis. Any change in size, shape, color or elevation of a spot on your skin, or any new symptom in it, such as bleeding, itching or crusting, may be a warning sign of melanoma. If you have cutaneous melanoma it is important to. Melanotan 2 lacks FDA approval yet many advocate for more research to study its effects on autism. Once used, they trigger melanogenesis, a process associated with the increased production of melanin. Nodular melanoma is a type of skin cancer. Add to cart. Some people may have melanoma without any pain or discomfort. Melanotan II, alpha-Melanocyte stimulating hormone, Melanotan peptid, or MSH is a synthetic variant of a natural peptide hormone that’s responsible for melanogenesis (a process that cause pigmentation of the skin) in the body. Melanotan-II is POSSIBLY SAFE when used under medical supervision for treating ED (erectile dysfunction). Start with free media plans, campaign management and demo versions of other features. There are many theories regarding AM pathogenesis. Darkened skin helps protect you naturally from the UV rays and helps reduce cancer. We guarantee delivery or full money back. This cancer typically occurs in areas that are only occasionally sun-exposed; tumors are most commonly found on the back in men and on the legs in women. Rather than develop a tan by spending excessive. There are 2 main categories of skin cancer. The most common sign of melanoma is the appearance of a new mole or a change in an existing mole. Buy Melanotan 2 10mg (MT2) | 99% Purity and USA Made. Oral melanoma is a very rare malignancy that progresses rapidly and proves to be particularly aggressive. We report a rare case of a patient presenting with priapism after subcutaneous injection of melanotan. Day 02 - 30 units - 1500mg - Injection 11:39pm - Symptoms: After 10mins: Slight redness at injection point. Treatment may include surgery, chemotherapy, immunotherapy, targeted therapy and radiotherapy. The authors write. Another measure that helps estimate the outcome of cancer is the prognosis, meaning your chances of recovery or recurrence. The skin is the body’s largest organ. Wide excision ( surgery to remove the melanoma and a margin of normal skin around it) is the standard treatment for stage II melanoma. 3K followers, 0 / mo - Tweets freq, and 0% - Engagement Rate. Nodular Melanoma. Melanotan II Side Effects. Nodular melanoma. It develops from skin cells called melanocytes. The risk of this type of melanoma may increase with age because of prolonged sun exposure. The disease typically begins in a mole and can occur anywhere on the body. This observation brings attention to the potential risks related to the use of the cyclic α-melanocyte-stimulating hormone analogue MT-II. Possible signs and symptoms of a melanoma include: “A” for asymmetry: An unevenness of a mole—when one half doesn’t match the other half—may be a sign of. To help the Melanotan 2 to dissolve roll the vial between your fingers NEVER SHAKE THE VIAL. Plant melampodium after all danger of frost has passed. Choroidal melanoma is a form of cancer that affects the choroid, part of the middle layer of the eye. Doctors refer to this stage as “melanoma in situ. But in most cases. A new spot on the skin or a spot that is changing in size, shape, or color is an important warning sign. Stage 0: Melanoma is localized in the outermost layer of skin and has not advanced deeper. Rarely, biopsies may be needed to figure out what type of cancer someone has. Existing mole that begins to change color, size or shape. But if you really want to tan, you. This case study presents a patient attending the accident and. 00 $ 79. Using Melanotan 2 nasal spray is easy. After 5 Months my skin has darkened as you'd expect after being a lot outside during summer, except it's the whole body. At the time they were developed by oncology. Form. 9% Pure Pharmaceutical Grade Melanotan 2, produced in the USA! Our state of the art labs individually vacuum seal sterile vials of 99. Radiation Therapy for Melanoma Skin Cancer. In a clinical study involving six males and one female, MT 1 treatment (0. Introduction. 10. In a study of 3,500 metastatic melanoma patients from 2000 to 2013, those diagnosed with metastatic mucosal melanoma had a. Oral melanomas are the most common malignant oral tumor in dogs. [] It is mainly found in sun-exposed areas of the skin, especially the head and neck (51%, [12, 13]). Side Effects of Melanotan 2 | Verdict. Evolving: The mole has changed over the past few weeks or months. Melanin is the substance in skin that produces skin pigment. It is one of the most aggressive and fatal forms of skin malignancy. Recurrent melanoma refers to a recurrence of a tumor at the site of removal of a previous tumor, such as in, around, or under the surgical scar. The highest price is $ 235. Carmela Anthony X (Twitter) Stats and Analytics. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Intranasal bremelanotide, an active metabolite of melanotan II, is presently in clinical trials in men and women, and showing promising results for inducing erection in men and sexual arousal in women ( Safarinejad and Hosseini, 2008; Safarinejad, 2008 ). [1][2] The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared. Based on the stage of the cancer and other factors, your treatment options might include: Surgery for Melanoma Skin Cancer. Full staging including CT scanning is recommended to. It starts off by growing along the top layer of the skin. The protective amino acid structure of tanning peptide Melanotan 2 influences sexual functions, energy, appetite, inflammation and pigmentation by binding to the Melanocortin 1, 3, 4, 5 receptors (MC1, MC3, MC4, MC5). It can look like a: Changing mole. The tumour is quite often diagnosed. Melanotan 2 (MT-2) or sometimes written as Melanotan II is a synthetic form of human α melanocyte stimulating hormone (α MSH). It occurs when pigment-making cells in the skin, called melanocytes, begin to reproduce uncontrollably. 11 reviews. – Headaches or seizures. Acral lentiginous melanoma is usually found on the palms of the hands and soles of the feet or around the big toenail. Melanotan II is a synthetic variant of the naturally occurring peptide hormone alpha-melanocyte stimulating hormone (α-MSH) 1, which acts to stimulate the production of melanin in the skin – the molecule responsible for hair and skin pigmentation – through a process called melanogenesis 2. These are found in the deepest part of the epidermis (the top layer of your skin). Facial pain. Melanotan II comes with a long list of possible side effects, including: Acne. Consider Melanotan injections for sale that will let you benefit from sunless tanning at its best. 5.